nayyarENT Thursday Grand Round no. 4

“51 yrs old male, teacher by occupation has reported with h/o hoarseness for past 2 mths, insidious onset, slowly progressive, with no difficulty in breathing or swallowing, no foreign body sensation. Has 4 kg weight loss in past 2 months. H/o cigarette smoking, 1 pack per day for past 25 yrs present”

1. Give your differential diagnosis.

2. What is field cancerization.

3. What are the types of conservative laryngectomies. Describe them.

4. What is chemoprevention.

5. How does tobacco cause cancer.